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That more than half of BRCA-negative women in this study chose bilateral prophylactic mastectomy, a procedure not recommended in this population, is concerning, and reflects nationwide trends.
Is BRCA testing causing women to undergo unnecessary prophylactic mastectomy?
The most common risk- reducing surgery is bilateral prophylactic mastectomy. This may involve complete removal of both breasts including the axillary lymph nodes (total mastectomy); removal of the breasts only with the axillary nodes intact (modified mastectomy); or removal of as much breast tissue as possible with the nipples intact (subcutaneous or nipple-sparing mastectomy).
Prophylactic surgery for breast cancer and alternative treatments
The data indicated that bilateral prophylactic mastectomy reduces the risk of breast cancer by approximately 90%.'
South Africa
In women who do have a genetic predisposition for breast cancer, we, at the Breast Centre, Llandough Hospital, do offer counselling and the options of wait and watch or bilateral prophylactic mastectomy. "I think it is very important for women to be self aware of any breast symptoms and seek advice if they are worried.
ANGELINA JOLIE has been praised [...]; SUPERSTAR ANGELINA PRAISED BY CAMPAIGNERS AFTER OP
Efficacy of bilateral prophylactic mastectomy in BRCA1 and BRCA2 gene mutation carriers.
Breast cancer after prophylactic mastectomy for Lobular Carcinoma-In-Situ (LCIS)--an unusual case
A population-based study of bilateral prophylactic mastectomy efficacy in women at elevated risk for breast cancer in community practices.
Cancer de mama asociado a mutaciones geneticas de los BRCA 1 y 2
However, among 90 patients undergoing bilateral prophylactic mastectomy, the rate of depression had not changed 1 year after the procedure.
Tailoring depression treatment for women with breast cancer: factors unique to these patients help determine treatment strategies
In fact, the only intervention of greater preventive efficacy in breast cancer is bilateral prophylactic mastectomy In addition, the safety profiles of these two agents are excellent.
The news is good; we need to get the word out
Let's look at the case of Rene Syler, former co-host of CBS' The Early Show, who, after evaluating her family history, underwent a successful bilateral prophylactic mastectomy to avoid breast cancer.
Black Women's journey to good health
Bilateral prophylactic mastectomy decision making: a vignette study.
Cirugia profilactica como medida preventiva del cancer de mama y ovario hereditario
SAN ANTONIO -- Long-term satisfaction with the decision to undergo bilateral prophylactic mastectomy with immediate breast reconstruction is often diminished by unanticipated changes in body image and the sexual relationship, Paula J.C.
Preventive mastectomy leaves mark on sexuality: breasts 'didn't feel like my own'
SAN ANTONIO -- Long-term satisfaction with the decision to undergo bilateral prophylactic mastectomy with immediate breast reconstruction is frequently diminished by unanticipated changes in body image and the sexual relationship, Paula J.C.
Sexuality suffers after prophylactic mastectomy: followed by immediate reconstruction

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