levels rose, so did the mice's ability to withstand pain.
More recently and due to improved testing techniques, the relationship between authentic beta-endorphin
and labour stress has not been established (Harbach et al., 2008).
production by the fetal Leydig cell: regulation and implications for paracrine control of Sertoli cell function.
concentration after administration of sucrose in preterm infants.
and other opioids are involved in restraint stress-induced stimulation of the hypothalamic-pituitary-adrenal axis, the sympathetic nervous system, and the adrenal medulla in the rat.
Continuous subcutaneous administration of high-dose salmon calcitonin in bone metastasis: pain control and beta-endorphin
So now beta-endorphin
joins the cohort of neuro-messengers such as the earlier discussed serotonin, both theorized to be involved in mood regulation and in pain transmission.
CRF causes the basophilic cells of the anterior pituitary gland to induce proopio-melanocortin, a polyprotein which is cleaved to form adrenocorticotropic hormone (ACTH) and beta-endorphin
. Opiates function to relieve pain during a fight-or-flight stress situation (Black, 1994).
For those who are unable to articulate their pain, such as infants, unconscious adults, or unborn children, the perception of pain must be deduced, indirectly, by observing other biological responses, such as a physical withdrawal of limbs from painful stimulus, a change in vital signs (blood pressure and pulse rate go up), or a release of stress hormones (cortisol beta-endorphin
 measured the circulating beta-endorphin
levels before and after exercise testing.
In a few promising studies, clinical investigators have injected an endorphin called beta-endorphin
under the membranes surrounding the spinal cord.
The popular idea of the "endorphin rush" was born in the 1980s and 90s, when a series of studies showed that the levels of beta-endorphin
increase in your bloodstream during the course of a run.