are also important for the treatment of arrhythmias and coronary artery disease, in which they have been shown to improve survival and reduce the risk of future heart attacks and hospitalizations.
It would be premature to recommend the use of beta-blockers
for these patients, until we conduct prospective clinical studies said Dr.
Patients who used beta-blockers
had higher SBP and DBP and more acceptable MAP values compared with patients who did not use beta-blockers
A 2013 stratified subset meta-analysis used data from landmark randomized controlled trials (RCTs) that evaluated beta-blockers
vs placebo in patients with systolic heart failure to compare metoprolol succinate (MERIT-HF) vs placebo with bisoprolol (CIBIS-II), carvedilol (COPERNICUS), and nebivolol (SENIORS-SHF) vs placebo (table).
are used to treat migraine as they counteract the effects of noradrenalin on blood vessels in the head.
therapy was initiated within one month of surgery in 12 (6.
Overall, the researchers found that adding beta-blockers
as the second-line drug, in combination with thiazide diuretics or calcium channel blockers, caused an additional blood pressure reduction.
Evidence supports beta-blocker
use in coronary artery disease and congestive heart failure.
Although patients on beta-blockers
in this study were older and more severely injured than were those not taking beta-blockers
, mortality rates for the two groups were similar, Dr.
efficacious as first-line therapy for hypertension in the elderly?
are certainly necessary in many patients who have coronary artery disease; however, an attempt should be made to adjust the dosage to allow attainment of at least 70% predicated maximal heart rate or keep heart rate levels below that which cause ST depression or angina.
However, I wanted to inform you that verapamil is not a beta-blocker
and, instead, is a calcium-channel blocker that produces its effects on the heart by blocking the transport of calcium into myocardial muscle cells, thus reducing excitability and contractility of the heart.