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The US Food and Drug Administration has granted both Breakthrough Therapy Designation and Orphan Drug Designation to US-based clinical-stage biopharmaceutical company PellePharm for topical patidegib for reduction of the life-long serious clinical morbidity and disease burden of persistently developing basal cell carcinomas in patients with Basal Cell Carcinoma Nevus Syndrome (BCCNS), a rare genetic disease also known as Gorlin Syndrome, the company said.
PellePharm Receives Breakthrough Therapy and Orphan Drug Designations from US FDA for Topical Patidegib for Patients with Basal Cell Carcinoma Nevus Syndrome
Basal cell carcinoma displays a variety of growth patterns that may be broadly divided into nonaggressive (indolent) and aggressive types.
Histologic Mimics of Basal Cell Carcinoma
There were 98 cases of basal cell carcinoma, 49 cases of squamous cell carcinoma, and 34 cases of malignant melanoma.
Chronic GVHD linked to fivefold increase in SCC
Classically, they are thought to arise from epidermal basal cell layer, although current theory supports either a follicular or interfollicular stem cell origin.
Aetiological, clinical and histopathological study of basal cell carcinomas- at Rangaraya Medical College, Kakinada
According to the Skin Cancer Foundation, basal cell carcinoma stems from abnormal, uncontrolled growths or lesions that appear in the skin's basal cells.
LOOK: Hugh Jackman seeks skin cancer treatment for 5th time
Cutaneous markers of photo-damage and risk of basal cell carcinoma of the skin: a meta-analysis.
Basal cell carcinoma of the skin: Topographic distribution and clinicopathological differences with regards to the extent of sunlight exposure
Keywords: Basal cell carcinoma; cytology; dog; pathology
Surgical Management of Basal Cell Carcinoma (BCC) in a Dog
In 2011, we removed a benign basal cell tumor from a wild born captive cheetah living on a Namibian farm.
Benign Pigmented Dermal Basal Cell Tumor in a Namibian Cheetah (Acinonyx jubatus)
The cells were arranged into well-demarcated islands and strands, which appeared to be raised from the basal cell layer of the overlying epidermis and invaded into the underlying connective tissue (figure 3).
Secondary involvement of the mandible due to basal cell carcinoma: a case report
Among these tumors, basal cell carcinomas are less common and less aggressive in nature.
Basal cell carcinoma of the external auditory canal
AbstractBasosquamous cell carcinoma is a subtype of basal cell cancer.
Bilateral lower eyelid basosquamous cell carcinoma: a rare case
USPRwire, Mon Jun 30 2014] Global Markets Direct's, 'Basal Cell Carcinoma (Basal Cell Epithelioma) - Pipeline Review, H1 2014', provides an overview of the Basal Cell Carcinoma (Basal Cell Epithelioma)'s therapeutic pipeline.
Market Report, "Basal Cell Carcinoma (Basal Cell Epithelioma) - Pipeline Review, H1 2014", published

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