in the female reproductive tract: influence of the estrous cycle on antigen presentation by uterine epithelial and stromal cells.
It is unclear if the defect is primarily a T-cell aberration or if it is due to an antigen-presenting cell
Evidence that cutaneous antigen-presenting cells
migrate to regional lymph nodes during contact hypersensitization.
Activation of cutaneous immunity by percutaneous absorption of chemical through the stratum corneum is well established; however, given the long dissolution half-life for beryllium metal and its alloys, we hypothesized that beryllium particles would have to colocalize with the cutaneous antigen-presenting cell
in the epidermis in order to activate a cell-mediated immune response.
24) Antigen-presenting cells
subsequently present processed antigen to naive T cells, leading to the differentiation to Th1 cells, Th2 cells, Th17 cells, and cytotoxic T cells; they also induce IgA-committed B cells ([IgA.
The latter cells bind to MHC I on the antigen-presenting cells
and destroy them, whereas the former contribute to immunological memory of the activation event.
In the laboratory, they cultured the proteins with dendritic cells, the immune system's most powerful antigen-presenting cells
, which are responsible for helping the immune system recognize and attack invaders.
Specialists in nanomedicine, nanotechnology, and translational bio-nanotechnology in academia, government, industry, consulting organizations, and regulatory agencies in the US, Europe, Australia, and India address topics such as nanoparticle interaction with erythrocytes, endothelial cells, various types of antigen-presenting cells
, complement activation, platelets and the plasma coagulation system, bone marrow cells, nanoparticle use for drug delivery and vaccine adjuvants, sterility and sterilization, the presence of surface contaminants, regulatory considerations for the screening of nanoparticle toxicity to the immune system, the use of animal models to study nanoparticle immunotoxicity, and material characterization.
The non-helper regulatory T cells, or the antigen-presenting cells
(APC), likely influence immunity in a manner comparable to Th1 and Th2 cells.
While the exact mechanism is unknown, a large numbers of studies have shown that Ganoderma may modulate many components of the immune system such as the antigen-presenting cells
, NK cells, T and B lymphocytesm, which are pivotal to initiating a primary immune response.
The thing that excites me most about this finding is that these immune cells appear to have 'memory' of the molecule brought forth by the antigen-presenting cells
," said Klaus Ley, M.
It's mimicking some of the native molecules, but this turns out to be specific to antigen-presenting cells
, endothelial cells, and monocytes," said Dr.