(11) Studies have shown that by stimulating production of acetylcholine, PS can improve the condition of patients experiencing age-associated memory impairment
or cognitive decline.
Prior to the PET scan, the working diagnoses in the 25 patients included probable Alzheimer's disease in 6, mild cognitive impairment in 5, depression in 4, age-associated memory impairment
in 3, frontotemporal dementia in 1, and dementia not otherwise specified in 1.
The debate about the clinical validity of age-associated memory impairment
(AAMI) as a disorder requiring treatment is perhaps less immediately clinically relevant, but the evidence is clearly presented for the reader to judge.
Subjects were 120 elderly (> 57 years) of both sexes who fulfilled the more stringent criteria for age-associated memory impairment
(AAMI); some also fulfilled the criteria for age-associated cognitive decline.
The patches have also been found to compare favorably with Ritalin in their ability to improve concentration in youngsters with attention deficit hyperactivity disorder (ADHD), and to boost recall in seniors with the mildest form of memory loss, called age-associated memory impairment
Considerable resources are implicated in a multidisciplinary memory clinic, and estimates of visits needed for diagnosis will help to: (i) determine selection points for psychometric testing, (ii) determine resource requirements for dementia assessment, and (iii) cast light on controversial disease entities such as age-associated memory impairment