Reduction in the value of an asset because the asset no longer generates the benefits expected earlier as determined by the company through periodic assessments. This could happen because of changes in market value of the asset, business environment, government regulations, etc.
Subjects were 120 elderly (> 57 years) of both sexes who fulfilled the more stringent criteria for age-associated memory impairment (AAMI); some also fulfilled the criteria for age-associated cognitive decline.
Prior to the PET scan, the working diagnoses in the 25 patients included probable Alzheimer's disease in 6, mild cognitive impairment in 5, depression in 4, age-associated memory impairment in 3, frontotemporal dementia in 1, and dementia not otherwise specified in 1.
The debate about the clinical validity of age-associated memory impairment (AAMI) as a disorder requiring treatment is perhaps less immediately clinically relevant, but the evidence is clearly presented for the reader to judge.