is a widely used rodent model in studies addressing rheumatoid arthritis owing to similarity of its pathological characteristics to human RA .
Li, "Experimental research on effect of qingpeng paste treating adjuvant arthritis
in rats," Chinese Journal of Experimental Traditional Medical Formulae, vol.
Sumbalova, "Effect of coenzyme Q10 supplementation in the rat model of adjuvant arthritis
," Biomedical Papers, vol.
It can not only inhibit destruction of joint structure but also improve health status in adjuvant arthritis
and ameliorate clinical symptoms, such as paw edema, granulation tissue hyperplasia and so on.
The therapeutic activity and adverse effects of three different glucocorticoids (dexamethasone, budesonide, and prednisolone) encapsulated in long circulating liposomes was determined in rats with adjuvant arthritis
and collagen-induced arthritis.
Table 2: Effect of methanolic extract of Gentiana kurroo on mycobacterium induced adjuvant arthritis
in 1st week.
Preventive actions of a high dose of glucosamine on adjuvant arthritis
Blood was collected and laboratory parameters (rheumatoid factor, CRP, total proteins, albumin, globulin, interleukin-2, interleukin-6) were measured in order to assess the successful induction of experimental adjuvant arthritis
. Commercial enzyme linked immunosorbent assay (ELISA) kits for the quantitation of IL- 2 and IL-6 were employed.
Durham, Inhibition of cartilage degradation in rat collagen-induced arthritis but not adjuvant arthritis
by the neutrophil elastase inhibitor MDL 101,146, Inflamm.
Classical animal models of arthritis such as adjuvant arthritis
or streptococcal cell wall arthritis are dependent on the TLR pathway activation (10).
Researchers also noted that the oral administration of beta-alanyl-L-histidinato zinc (AHZ) or zinc acexamate has a restorative effect on bone loss under various pathophysiologic conditions including aging, aluminum bone toxicity, calcium and vitamin D deficiency, adjuvant arthritis
, estrogen deficiency, diabetes, and fracture healing.
Its administration has been (Continued on next page) able to suppress almost all experimentally inducible forms of rheumatoid arthritis in animals, including antigen-induced arthritis, adjuvant arthritis
, undenatured type II collagen-induced arthritis, streptococcal cell-wall arthritis, and silicone-induced arthritis.