Taken together, these ways to address undifferentiated cell
contamination in iPSC-derived NS/PC transplants are, at least in part, currently effective, but it seems impossible for some of these methods to be translated into clinical application due to either the invasive operation or time-consumed culture to weaken epigenetic memory.
They found one newly generated antibody that was highly specific for a previously unknown marker on undifferentiated cells
that they termed stage-specific embryonic antigen-5, or SSEA-5.
Previous studies [11, 12] have proposed that undifferentiated cells
are involved in myometrial pathologies, and also leiomyoma onset may be the result of impaired function, proliferation, and differentiation of undifferentiated cells
inside the myometrium that are under the effect of ovarian hormones [13,14].
OCT4B1 is highly expressed in undifferentiated cells
and down-regulate during cell differentiation (7).
6-1) Discovery of the undifferentiated cell
zone between zG and zF of the rat adrenal cortex.
Cord blood is being used increasingly on an experimental basis as a source of stem cells, which are undifferentiated cell
capable of turning into specialized types of cells.
myoblast: An undifferentiated cell
in an embryo that is a precursor of a muscle cell.
An undifferentiated cell
has the capacity to remain a stem cell until directed to become another type of cell such as a cardiac cell, beta (insulin producing) cell, nerve cell and others.
ES cells can be maintained in culture as undifferentiated cell
lines or induced to differentiate into many different lineages (7).
Adult stem cell: An undifferentiated cell
found in a differentiated tissue that can renew itself and (with certain limitations) differentiate to yield all the specialized cell types of the tissue from which it originated.
Thus, all morphological intermediate stages may be observed in the molluscan heart-from small oval cells with no or only a few myofilaments to well-differentiated cardiomyocytes-and a series of cells representing the process of transformation of undifferentiated cell
into mature muscle cell can be identified.
JGCT of the testis is a rare, benign, subset of sex cord-stromal tumours which also include Leydig cell, Sertoli cell and undifferentiated cell
tumours.[sup.6] In the ovary, the adult form is much more common than the juvenile form; in the testis, the juvenile form is more common than the adult one.[sup.7] The JGCT of the testis has a tendency to occur in very young patients, mostly in the first 6 months of life.[sup.7] Ninety percent are found in infants of less than a year old.[sup.1]