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The clinical significance of these results is that undergrading of some prostate cancer needle biopsies appears to have occurred while the proportion of cases with Gleason scores 2 through 4 was declining more rapidly at NCI-designated programs and academic programs than it did at community programs and comprehensive community programs.
However, several studies investigating the correlation between Gleason scores in needle biopsies and corresponding radical prostatectomy specimens indicated that undergrading of carcinoma in needle biopsies is the most common problem, which were encountered in 42% of cases.
undergrading of tumors or composite tumors such as oligoastrocytoma in which only one component may have been sampled) were not considered discrepant as long as the general tumor cell type was consistent between FS and final diagnosis.
His low Gleason score may have been an undergrading since, for general pathologists, the main difficulty with the Gleason score system is undergrading.
It is also used as an ideological tool designed to represent the ideologies of non-conformity within narratives of individual characters to the views contained in the collective narratives of individual characters to the views contained in the collective narrative authored by, and undergrading the 'communal' lives of Africans living under colonial dominance.
Literaturle olan farklilik histopatolojik degerlendirmenin biyopsi materyali olmasi, biyopsideki undergrading ve retrospektif calisma olmasiyla aciklanabilir.
Producers accused grain elevator operators of dishonest weighing, of imposing high dockage charges, and of undergrading, allegations that had a definite basis.
When low-grade prostate cancer is diagnosed on needle biopsy, there is a risk of undergrading because of sampling error, which occurs when a higher-grade component in the prostate gland is not sampled during the biopsy process, which is highlighted in studies that correlate agreement between biopsy grade and subsequent final grade in the paired radical prostatectomy specimen.
Although undergrading biopsy GS is the most common problem,[sup.
The rates of overgrading and undergrading were respectively 42.
The changes recommended in the ISUP 2005 modified Gleason scoring system were intended to decrease the tendency toward undergrading observed in biopsies, when compared with radical prostatectomy specimens, and when the ISUP 2005 modified Gleason scoring system is used, some cancers receive higher scores than they would with the classic system.
In the few discordances, there was more frequent undergrading than overgrading (60.
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