Hydatiform moles are the most prevalent forms which are classified into Partial Hydatiform Mole (PHM) and Complete Hydatiform Mole (CHM)3, when choriocarcinomas and invasive moles are rare forms of gestational trophoblastic disease
Erroneous reporting of proficiency test results will thus reflect errors in reporting of patient results that could cause misdiagnosis and mismanagement of trophoblastic diseases
, although such errors may not affect the diagnosis of normal pregnancy, in which both intact hCG and total [beta] hCG increase dramatically (4, 5).
Gestational trophoblastic disease
(GTD) consists of a variety of disorders that arise from placental trophoblastic tissue.
13) Gestational trophoblastic disease
(GTD), particularly in patients with associated uterine arteriovenous fistula, may also have similar US findings of increased uterine vascularity with a low RI.
OBSERVATION & RESULTS: Out of 82 cases of GTD, 77 were hydatidiform mole, one was invasive mole, 2 were persistent trophoblastic disease
and 2 were choriocarcinoma.
HCG tests in the management of gestational trophoblastic diseases
DISCUSSION: Gestational Trophoblastic Disease
(GTD) is a term used for a group of pregnancyrelated tumors.
For hCG, assay sensitivity need not be extremely high for conventional pregnancy detection, but sensitive and quantitative assays can also contribute dramatically to the prompt diagnosis and management of urgent disorders, such as ectopic pregnancy in patients with acute abdominal pain or vaginal bleeding (17,18), as well as threatened abortion and gestational trophoblastic disease
An unusual presentation of gestational trophoblastic disease
Although equal recognition of hCG, hyperglycosylated hCG, and hCG[beta] is generally desirable, it is also known that separate and specific determination of hCG and hCG[beta] may facilitate detection of high-risk trophoblastic disease
INTRODUCTION: Molar pregnancy is a gestational trophoblastic disease
In patients with trophoblastic disease
, even greater between-method variation has been observed.