(7), atypical antipsychotics were not found, similar to our findings, to be safe compared with typical antipsychotics in toxic doses
. Severe clinical findings were observed in a patient poisoned by the most exposed atypical antipsychotic, quetiapine, in our study.
persica was investigated especially at the minimal toxic dose
levels of 10 and 20 [micro]g/ml.
Four years ago, scientists reported that in rats, large doses of vitamin A transform minimally toxic doses
of carbon tetrachloride into a potent liver poison.
"Our estimate is that as many as 10 percent of the children in the American Southwest have potentially been exposed to a toxic dose
[of lead]," Trotter reported this month at a conference on advances in lead research, convened by the National Institute of Environmental Health Sciences in Research Triangle Park, N.C.
With pharmaceuticals, there's always a considerable gap between the dose you're warned not to exceed and a potentially toxic dose
. However, with a lot of herbs, the toxic dose
isn't known simply because the research hasn't been done.
Cough medicines traditionally contain more than one ingredient and if a parent doubled up with another product, the toxic dose
of one of them could be given accidentally to a baby.
He added: "There is very little difference between the effective dose and the toxic dose
of most anaesthetics.
Our laboratory has previously shown that a single, low, nonovertly toxic dose
of arsenite can significantly and preferentially alter both the basal and inducible mRNA expression of the model hormone-inducible phosphoenolpyruvate carboxykinase (PEPCK) gene, both in whole-animal and in cell-culture models (8).
Therefore, a method is needed to overcome these problems without the use of toxic doses
. Iron oxide nanoparticles can be used as a drug delivery system.
The two groups (G1 and G2) were given toxic doses
of simvastatin (60mg/kg/day) with and without Co Q10 (5mg/kg/day) orally for 14 days and rest of two groups (G3 and G4) were kept on therapeutic doses (1mg/kg/day) of simvastatin with and without Co Q10 (5mg/kg/day) orally for 90 days.
Treatments would require huge, toxic doses
to affect the course of the infection.
The last time I expressed concern about a patient's allergy to any pain medication--except oxycodone and the potentially toxic doses
of ibuprofen and acetaminophen that didn't "touch it"--I was the recipient of seething rage and hostility.