The discordant result between CLIA and RPR was seen in 121 (78.06%), among which 10 (6.45%) were confirmed positive by
TPHA. The 10 (6.45%) cases of syphilis detected by CLIA would have been missed if RPR was the initial screening test.
Sen, "A comparative study of clinically suspected syphilis cases with serological test VDRL/RPR & Treponema pallidum hemagglutination assay (
TPHA) in a tertiary care hospital (Silchar Medical College & Hospital)," Journal of Science, vol.
TPHA was positive for 7 out of 34 WB indeterminate samples with s/co ratios lower than 15.17, one of which was also positive by RPR.
These three cases were screened reactive by the CIA but were not confirmed by the
TPHA test.
The participants were screened for syphilis with the RPR and
TPHA tests.
The erythrocyte sedimentation rate was high, but the serology tests for IgM, IgG HSV 1-2, HIV, CMV, HBV, HCV,
TPHA were all negative.
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In:
TPHA. Sector reforms and health in Tanzania, p.213-230.
A
TPHA test was performed in every case to rule out cross-reacting antibodies to Treponema pallidum.
At a routine medical examination 5 months earlier, serum rapid plasma reagin (RPR) and treponema pallidum hemagglutination (
TPHA) were negative.
HIV-I: Reactive, HBsAg: Reactive; CD4: 385.08 cells/cmm; CD8: 934.4 cells/cmm; CD4:CD8 Ratio= 0.41; Ultrasound Abdomen: no organomegaly; HSV IgG Antibodies: 3.33 (Significant >1.5); Tzank smear: negative; Tissue smear for grams stain: no bacteria; VDRL: non-reactive;
TPHA: negative; Mantoux test: negative; Blood for TB PCR: negative; Biopsy: Aphthous ulcer.