Cycle

(redirected from TCA cycle)
Also found in: Dictionary, Thesaurus, Medical, Encyclopedia, Wikipedia.

Cycle

Farlex Financial Dictionary. © 2012 Farlex, Inc. All Rights Reserved
References in periodicals archive ?
The CS is the first enzyme in TCA cycle. Zhang et al [33] reported that the increased Asn could stimulate the CS activity.
The decrease of TCA cycle metabolites such as succinate is also because of mitochondrial impairments which lead to energy deficiency (45,46).
This serves multiple purposes to set the stage for a catabolite-mediated adaptive response that feeds key metabolites into the TCA cycle. This response allows yet another set of subpopulations to survive long enough for abolished production of OmpK36, which leads to diminished cell entry of the drug and therefore high-level CR.
In the last decades, several studies provide evidence that supports the interaction between CAD and TCA cycle. For example, the degradation of myocardial aspartate and glutamate is induced by the complete citric acid cycle, ischemia, and hypoxia.
SDH and FH participate in sequential reactions in the TCA cycle catalyzing the conversion of succinate to fumarate and fumarate to malate, respectively (Fig.
Ketone bodies, including acetone and acetoacetate, were produced by the liver from fatty acids and then converted into acetyl-CoA which then enters the TCA cycle. In case of fasting, starvation, or enhanced fatty acids beta-oxidation, synthesis of ketone bodies was upregulated [39].
The results of our pathway topology revealed the dysfunction of the TCA cycle; alanine, aspartate, and glutamate metabolism; and steroid hormone biosynthesis in CFS rats.
Camacho-Pereira et al., "HSulf-1 deficiency dictates a metabolic reprograming of glycolysis and TCA cycle in ovarian cancer," Oncotarget, vol.
Glutamine is taken up by the mitochondria and transformed into glutamate, which can be converted into [alpha]-ketoglutarate and support oxidative metabolism in the TCA cycle. Absolute and relative OCRs of isolated whole-brain mitochondria from control and db/db mice are presented in Figure 2.
Cells were grown to 80% confluency on 10 cm dishes before performing the extraction of the TCA cycle intermediates.
Citrate, the intermediate of TCA cycle, was accumulated in the myocardium; while coenzyme Q, the key enzyme of energy metabolism, and pyridoxine, an essential vitamin related to ischemic heart disease, were significantly decreased.
The TCA cycle is a key metabolic hub for the interacting pathways of N assimilation and respiration metabolism (Foyer et al., 2011).