Uses and limitations of quantitative structure-activity relationships
(QSARs) to categorize substances on the Canadian Domestic Substance List as persistent and/or bioaccumulative, and inherently toxic to non-human organisms.
Extended quantitative structure-activity relationships
for 80 aromatic and heterocyclic amines: structural, electronic, and hydropathic factors affecting mutagenic potency.
A comparison of model performance for six quantitative structure-activity relationship
packages that predict acute toxicity to fish.
have been carried out and their structure-activity relationships
(SAR) also studied.
This is important because a QSAR model's ability to predict unknown chemicals depends largely on the nature of the training set and the algorithm used to establish the structure-activity relationship
(Eriksson et al.
Part I: Structure-Based Design and Structure-Activity Relationship
Studies" and "Discovery of Piperidine-4-Carboxamides as Potent Chemokine Receptor CCR2b Antagonists.
They agreed, especially industry and regulatory authorities, that the workshop initiated great potential for the further development and use of predictive models, that is, quantitative structure-activity relationships
[Q)SARs], for chemicals management in a much broader scope than is currently the case.
SAR refers to structure-activity relationships
, where the term activity can refer to any property, or even to a collective score that represents many properties like our ADMET Risk score in ADMET Predictor.
Hydroxylated polychlorinated biphenyls (PCBs) as estrogens and antiestrogens: structure-activity relationships
The combination of Eurofins Pharma Discovery Services and DiscoverX provides the pharmaceutical and biotech industries with a partner of choice for end-to-end drug discovery services, enabling customers to improve research productivity and effectiveness of their screening, lead optimization and structure-activity relationships
(SAR) campaigns, thus accelerating the discovery and development of new drugs.
Eurofins said that a combination with DiscoverX provides the pharmaceutical and biotech industries with a partner of choice for end-to-end drug discovery services, enabling customers to improve research productivity and effectiveness of their screening, lead optimisation and structure-activity relationships
campaigns, thus accelerating the discovery and development of new drugs.
Quantitative structure-activity relationships
for joint toxicity of substituted phenols and anilines to Scenedesmus obliquus.