As aromatase inhibitors deprive post-menopausal women of oestrogen, menopausal effects are exaggerated, The main side-effects are hot flushes, arthralgias and myalgias, reduced libido, a dry vagina and skin, and thinning of hair.
This drug is also administered to post-menopausal patients, with the same side-effects as in pre-menopausal women, except for the menstrual changes.
MDT introduction met with considerable resistance in Brazil because of a significant risk of side-effects. (11-14) Despite this, in 1991, MDT was adopted as the sole treatment for leprosy patients in Brazil.
A wide range of frequency of side-effects caused by MDT has been reported from Brazil.
Hormone therapies like Tamoxifen and Goserelin tend to be viewed as a gentler option for patients - but the report today revealed that up to 99 per cent of women suffered side-effects.
Women must be fully informed of the benefits and all possible side-effects of treatments.
Dr Jacobo Mintzer, of the Medical University of South Carol na, said: "Those in nursing homes may rely upon care staff to alert the physician to side-effects.
"Informing patients and carers about potential side-effects is of great importance.
The most common side-effects
for Relenza - which is being given to pregnant women - include a cough and ear, nose and throat infections.