is estimated to cause 1.2 million human illnesses, 23,000 hospitalizations, and 450 deaths in the United States each year (1).
are nationally notifiable (12).
They did this by performing fecal transplants, which involved giving mice antibiotics to kill off their usual composition of gut bacteria and then replacing the microbial community with the feces of other mice, some of whom were resistant to Salmonella infection
. Then, the researchers determined which microbes were responsible for increased resistance to Salmonella infection
by using machine-learning tools to identify which groups of bacteria were different between the strains.
Therefore, reducing the available amount of TNF-alpha would inhibit the activation and differentiation of macrophages and thus increase the risk of disseminated Salmonella infection
. The various TNF-alpha antagonizing medications have slightly different formulations with different administration patterns and dosages.
This highlights the importance of cultures and sensitivities for not only definitively diagnosing a Salmonella infection
but also directing appropriate antibiotic management and stewardship.
A multidisciplinary approach is needed to treat immunocompromised patients with extraintestinal salmonella infections
(2008) Multistate outbreak of human Salmonella infections
associated with exposure to turtles--United States, 2007-2008.
She added: "Anyone who is concerned about symptoms suggesting salmonella infection
should contact their GP or out of hours service in the first instance."
Diabetes mellitus has been found to be associated with 28% of focal salmonella infections
AbstractObjectives: To determine the incidence and resistance pattern of Salmonella infection
in healthcare workers and their dependents.Methods: The retrospective analysis was conducted at Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, and comprised records of employees and their dependents with bacteraemia from January 2007 to December 2011.
The vulnerability to salmonella infections
is commonly believed to be due to generalised immunosuppression by malaria, whereby the entire immune system is weakened and compromised.
News of the recent emergence of the multidrug-resistant Kentucky strain of Salmonella, which has a high level resistance to ciprofloxacin (a common treatment for severe Salmonella infections
), focuses attention once again on the need for vigilance to prevent its further spread.