The accuracy of SDA-based SNP analysis
relative to DNA sequencing was demonstrated by genotyping the six targeted [[beta].sub.2]AR loci (-654, -367, -47, +46, +491, and +523) in 19 different blood specimens from 14 healthy volunteers and by analysis of cloned target nucleic acid.
The SNP analysis
of the 242 isolates resulted in 1,488 core-genome SNPs.
new to SNP analysis
a firm ground on which to build up expertise in
This is particularly useful for high-throughput research laboratories, allowing the integration of SNP analysis
into existing aCGH workflows.
But with its acquisition of Orchid Biosciences' genotyping instrument business last year (see IBO 12/31/02), Beckman Coulter now owns the technology that it had sold for SNP analysis
with its products.
Sessions will include SNP analysis
, disease markers, high-throughput protein analysis, and microarrays.
Now that human genome sequencing approaches success, many new opportunities exist for SNP analysis
, and Orchid has developed new analysis techniques and technologies to be applied to SNPs, including a microfluidics chip designed to enable bench level reactions with less reagent than originally required.
will also experience tremendous growth.
Based on the Company's patented Pyrosequencing(TM) technology, the product provides rapid and accurate genetic analysis and offers a high capacity, cost-effective solution for SNP analysis
and Tag sequencing -- the analysis of short DNA sequences used for genetic identification.
of the isolate from the patient described in this study (LN 2016) with 7 other M.
CLOURE: Clustal output reformatter, a program for reformatting ClustalX/ClustalW outputs for SNP analysis
and molecular systematics.