Microscopically, the mass was composed of hypercellular areas of
reticular cells arranged in nests and separated by connective tissue.
Lesions with a presumed fibroblastic, (1) myofibroblasts ("splenic inflammatory myofibroblasts tumor"), (1,2,20,21) fibroblastic
reticular cell (FBRC), (17) or "fibrohistiocytic" phenotype have been reported.
(c) In the lymph node cortex, ATX is expressed by fibroblastic
reticular cells and generates LPA locally.
Overall, these data indicate that conservation exists between human and planarian cytokine-like molecules that could be secreted by
reticular cells. These data also suggest a link between cytokine-like activity and infertility in planarians.
Moreover, CD146-positive cells were also identified in human bone marrow in situ, on adventitial
reticular cells located abluminally covering and stabilizing blood vessels, but not on erythroid or myeloid cells, endothelial cells, adipocytes, osteoblasts, osteocytes, or endosteal cells [15,16].
At 16 weeks clear cortico-medullary differentiation, interlobular septa with blood vessels and aggregations of small eosin stained masses of epithelial
reticular cells indicating early stage in the formation of Hassalls's corpuscles were observed (Fig.
Mice getting fibroblastic
reticular cells were much more likely than others to survive sepsis--a finding that brightens prospects for developing an effective treatment for the condition.