Lifestyle factors rarely, if ever, cause recurrent pregnancy loss
, but the following factors may increase the risk of miscarriage: obesity, high daily caffeine intake, alcohol consumption, use of nonsteroidal anti-inflammatory drugs, and social class and occupation.
When peripheral mononuclear cells from women who have recurrent pregnancy loss
were incubated with progesterone or dydrogesterone in vitro, T-helper 1 cytokine interferon-gamma decreased, while T-helper 2 cytokines such as interleukin-4 and interleukin-6 markedly increased, further documenting the importance of this cytokine ratio.
Our study proved that hypothyroidism is common problem in recurrent pregnancy loss
The causes of spontaneous abortion and recurrent pregnancy loss
include genetic, anatomical, infectious, immunological, endocrine and occupational etiologies (1, 5, 6).
In the present prospective study, it was found that high levels of serum VEGF were seen in the serum of the normal pregnant females in comparison to the serum VEGF levels of females with Recurrent Pregnancy Loss
. In many other studies, the VEGF levels were found to be higher in the Recurrent Pregnancy Loss
females in comparison to the normal pregnant females.
Factor V Leiden mutation in women with early recurrent pregnancy loss
: a metaanalysis and systematic review of the causal association.
Recurrent Pregnancy Loss
: Recurrent Pregnancy Loss
In our study, hypothyroidism was found to be significantly associated recurrent pregnancy loss
(P < 0.05).
How is recurrent pregnancy loss
(RPL)  defined and what is its frequency?
When different red cell sizes are observed (anisocytosis) in the peripheral blood smear, RDW values are elevated and this elevation is said to be associated with recurrent pregnancy loss
With that in mind, surgical intervention remains the standard of care for those with Mullerian duct anomalies suffering from recurrent pregnancy loss
or poor pregnancy outcomes .
Th17 and regulatory T cells in women with recurrent pregnancy loss
. Am J Reprod Immunol 2012;67: 311-318, doi: 10.1111/ j.1600-0897.2012.01116.x.