Its approach, called Progenitor Cell
Activation uses combinations of small molecule drugs to activate progenitor cells
within the body to create functional tissue.
Bakri, "The role of endothelial progenitor cell
in cardiovascular disease risk factors," Acta Medica Indonesiana, vol.
The journal Hypertension Research reported finding an increase in endothelial progenitor cells
and a decrease in free radicals in association with supplementation with taurine and magnesium.
Activated adult microglia influence retinal progenitor cell
proliferation and differentiation toward recoverin-expressing neuron-like cells in a co-culture model.
Presently, Progenitor Cell
Therapy produces ICT-121, a dendritic cell vaccine targeting CD133 cells, in a Phase 1 clinical trial for recurrent glioblastoma multiforme based on a Services Agreement between the firms.
(1) entitled "Endothelial progenitor cells
(CD34+KDR+) and monocytes may provide the development of good coronary collaterals despite the vascular risk factors and extensive atherosclerosis." The authors evaluated simultaneously the effects of endothelial progenitor cells
(EPC) and inflammatory cells on the presence and the extent of coronary artery disease (CAD) and the grade of coronary collateral growth in patients with clinical suspicion of CAD.
Under the agreement, NeoStem will issue a total of 11.2m ordinary shares and purchase warrants for between 1m and 3m extra shares in exchange for the membership interests of Progenitor Cell
populations in the periodontal ligament of mice.
Said Eigen, "Progenitor Cell
Therapy had been planning to relocate from its eurrent location at the Hackensack University Medical Center for over a year, but could not find an existing laboratory facility that met its needs.
Therapy is the perfect partner for us due to the importance they have placed on solving the logistical challenges of cell therapy commercialization," said Flora.
At the moment, it seems futuristic to envision therapy with progenitor cell
grafts that can survive without proliferation, integrate at appropriate sites, receive innervation, and perform well enough to restore basic mechanoelectrical transduction.
(CBMG) announced that its off-the-shelf allogeneic adipose-derived mesenchymal progenitor cell
(haMPC, "AlloJoin") therapy for knee osteoarthritis (KOA) has been approved as the first stem cell KOA drug application in China for a Phase 2 clinical trial.