[49.] Recommendation from Scientific Committee on Occupational Exposure Limits for Platinum and Platinum compounds
Coluccia et al reported that platinum compound
of acyclovir (antiviral drug) had anticancer properties, and had broader and stronger effect than acyclovir and had the same effect as cisplatin among anticancer properties (32).
An opening overview is followed by 41 contributions by 147 international researchers organized into four sections covering novel platinum analogues, original formulations and other heavy metals; cellular transport and intracellular trafficking of platinum compounds
; DNA damage and signal transduction--recognition/repair and cell- response; and clinical applications.
Cisplatin and other platinum compounds
are used in the treatment of cancers of the bone, connective tissue and muscles, brain and nerve tissues, head, neck, lungs, eyes, kidneys, adrenal glands, lymph tissues, liver, and reproductive organ tissues (see Figure 1) (CureSearch, National Childhood Cancer Foundation, & Children's Oncology Group, 2008; Mayo Clinic, 2008).
Washington, December 31 (ANI): Scientists at a leading European medical university have found out why chemotherapy using cisplatin often lead to hearing problems, but a treatment with oxaliplatin rarely does, despite both drugs being platinum compounds
, fluoropyrimidines, anthracyclines, etoposide, mitomycin C and, recently, taxanes and irinotecan are the most active drugs.
Satraplatin is a member of the platinum family of compounds, but unlike platinum compounds
currently on the market, satraplatin is orally administered.
But doctors began to notice that taxol could make a difference if it was given together with existing treatments, which use platinum compounds
In his thesis work, Bartlett had noticed that many reactions in which platinum or platinum compounds
had been fluorinated yielded a sublimable, red solid.