According to Jones, dielectrophoresis allows him to "rapidly dispense a large number of droplets on a substrate with just a simple structure." This system can form 25 or morn droplets of 50
picoliters or less in a linear array.
On-chip single-copy real-time reverse-transcription PCR in isolated
picoliter droplets.
These fluid delivery devices are also manufactured with accurate deliveries of
picoliter, nanoliter, microliter, and milliliter flows.
The polymerase chain reaction has evolved from gel analysis to real-time PCR to, most recently, digital PCR, where individual targets are amplified in
picoliter to nanoliter volumes and statistics are used to calculate target concentrations instead of standard curves or internal controls.
The device allows
picoliter to nanoliter volumes to be measured with high sensitivity without sacrificing spatial resolution, making it suitable for capillary LC and CE systems.
Picoliter and nanoliter quantities of reagents don't pose nearly the safety concerns that liter quantities of toxic or flammable chemicals do.
It also features "waterfall" technology, which prints millions of 1.2
picoliter droplets through each CMYK printhead.
With it, computer-coupled micromachined sensors enable rapid, comprehensive, high-precision analyses of biochemical samples measured in
picoliter volumes.
It features a three
picoliter drop size to help ensure smooth gradients and vignettes, life-like flesh tones, a four-level gray scale, provides a solid white in a single shot, and has an expanded color gamut.
Droplet microfluidics systems are used to make, manipulate, and analyze nanoliter to
picoliter droplets (18,21), which enable simple dPCR work flows that produce highly sensitive mutation detection within complex DNA mixtures (22, 23).
