Thus, it is possible to find bacteria flora associated with phosphorus metabolism with the model of using phosphate binder
. In this study, we took advantage of the model of 'phosphate-binder therapy' to perform a longitudinal study, to observe the change of microflora.
* Avoid calcium-based phosphate binders
in patients with known vascular calcifications.
The use of phosphate binders
in order to decrease phosphate levels diminishes the incidence of metastatic calcifications (12, 13).
dos Reis et al., "Disturbances of Wnt/[beta]-catenin pathway and energy metabolism in early CKD: effect of phosphate binders
," Nephrology, Dialysis, Transplantation, vol.
Rodriguez et al., "The effect of phosphate binders
, calcium and lanthanum carbonate on FGF23 levels in chronic kidney disease patients," Clinical Nephrology, vol.
Education regarding the importance of phosphate binders
and compliance with medication was provided by dialysis nurses and patient participation was tracked on a "Tally board" within each unit.
Amount of Fluid Ingested with Phosphate Binders
in Hemodialysis Dependent Chronic Kidney Disease (HDD-CKD) Patients (Abstract).
Ilypsa's lead drug candidate, ILY101, is a phosphate binder
for the treatment of hyperphosphatemia in CKD (chronic kidney disease) patients on hemodialysis.
Renvela is being developed as a next generation phosphate binder
to replace Renagel (sevelamer hydrochloride), the most-prescribed phosphate binder
in the United States.
Fosrenol(R) is a non-aluminium, non-calciumbased phosphate binder
and is sold around the world in 15 countries, including the US, Taiwan, Korea, Germany Sweden, Denmark, Austria and Ireland.
"We are very encouraged by the outcome of our Phase 1 study, and believe that ILY101 has the potential to offer an improved treatment option to patients who require chronic phosphate binder