independently predicts poor prognosis in patients with conditions including gastric cancer, pancreatic cancer, ovarian cancer, colorectal cancer, non-small cell lung cancer, hepatocellular carcinoma, renal cell cancer, and esophageal cancer (16).
NLR, MPV and PLR
values obtained from proportioning CBC parameters are potent predictors for the differential diagnosis of appendicitis from FMF and ML, which are the diseases confused most commonly with appendicitis.
Interrater agreement was higher with automated methods for pupil size, anisocoria, and PLR
. By excluding normal findings to analyze only the occurrences of detected anisocoria and abnormal PLR
, automated pupillometry still outperformed manual assessment.
Several clinical studies showed that high PLR
correlates with worse clinicopathological features in patients with HCC (26,27).
The CBC parameters included WBC, N, L, NLR, MPV and PLR
were recorded before six gestational weeks.
The mean lymphocyte count was significantly higher among the controls, and the mean PLR
was significantly higher among the women with PTBs (Table 1).
Inflammation is crucial in prostatic carcinogenesis and tumor progression by immune cell infiltration in prostate tissue and fibroblast activation along with several different mechanisms (4, 17) The NLR ratio and PLR
are inexpensive and practical parameters that can be checked by one CBC during routine clinic visits.
The prognostic value of preoperative NLR, d-NLR, PLR
and LMR for predicting clinical outcome in surgical colorectal cancer patients.
(20) found significant relationships between both NLR and PLR
ratios and LNI, whereas there was no significant relationship between WBC count and LNI.
Since the study purpose was to assess the implications of a primary elevation of NLR and/or PLR
, patients with rheumatic diseases, inflammatory bowel disease, recent surgery, chronic renal or liver disease, inherited thrombophilia, infection, or other possible secondary causes of altered ratios were excluded from the study.
The results of consecutive complete blood tests showed that the NLR and PLR
values of 7.05 (N: 84%, L:11.9%), and 407.5 (P: 326, L: 0.8x[10.sup.9]/L), respectively, on preoperative Day 1 decreased to 4.35 (N: 74%, L: 17%) and 380 (P: 266, L: 0.7x[10.sup.9]/L), respectively, on postoperative Day 5 and to 2.63 (N: 65.2%, L: 24.7%) and 251 (P: 277, L: 1.1x[10.sup.9]/L), respectively, on postoperative Day 14.