The nucleus pulposus
is posterior in the annulus and the posterior longitudinal ligament (PLL) is midline, creating a somewhat weak point in the annulus on either side of the PLL (Fig 5).
Autologous nucleus pulposus
induces neurophysiologic and histologic changes in porcine cauda equine nerve roots.
These risks and uncertainties include that results obtained from other studies of BioDisc may not support the potential use of BioDisc as a durable nucleus pulposus
replacement in spinal disc repair.
Experts in the field explored the benefits of minimally invasive surgery, motion sparing technology, nucleus pulposus
replacement and the disk regeneration.
One of the genes in particular forms a protein that is critical to the function of the nucleus pulposus
Endoscopy product development will seek to strike a balance between a minimally invasive flexible endoscope and effective instrumentation for removal of diskal nucleus pulposus
Objective: We hypothesize that within the intervertebral disc (IVD), a niche exists comprising the nucleus pulposus
and the inner layer of the annulus fibrosus and the cartilage endplate.
The increase in disc height was due to restoration in the transplant group of the nucleus pulposus
structure, which refers to the jelly-like substance in the disc, and an increased amount of water content, which is critical for the appropriate function of the disc as a cushion for the spinal column, the researchers concluded.
The disc joint is composed of three major parts: cartilaginous vertebral endplates that cap the bodies of the vertebrae, a fibrous annulus fibrosus that is located circumferentially between the vertebral bodies, and a thick gel-like nucleus pulposus
in the center bounded by the fibers of the annulus fibrosus.
In a proof-of-concept study published online in the journal Biomaterials, graduate student Aubrey Francisco and biomedical engineering professor Lori Setton describe a new biomaterial designed to deliver a booster shot of reparative cells to the nucleus pulposus
, or NP--the jelly-like cushion naturally found between spinal discs.
If you perform an activity that stresses the spine in a particular direction the Nucleus Pulposus
forces its way through the Annulous Fibosis.
Later chapters describe techniques such as provocation and analgesic discography, the use of intradiscal biologic agents, radiofrequency and other heat applications, and nucleus pulposus