While investigating for probable clues to suggest TB, it has been evident that in some patients, the Mantoux test
and CSF TB-PCR can become negative.
demonstrated an induration of 28 mm at the end of 72 hours (N < 10 mm).
Tuberculosis may present with pancytopenia, features of hemophagocytosis in bone marrow, and negative Mantoux test
does not rule out the diagnosis.
Though it is well established that Mantoux test
should not be used as a diagnostic tool in adults still 16(31.4%) clinicians felt that Mantoux test
result can be considered for initiating treatment.
Kumar et al3 and Pandhi et al8 have observed very high rates of Mantoux test
positivities in their
Screening for TB involves a simple skin test - a Mantoux test
- which is examined two to three days later and will show whether someone has been exposed to the TB germ.
Routine biochemical and hematological investigations, Mantoux test
and chest X-rays were done for all patients.
The aim of this study is thus to highlight any cases of tubercular infection in order to measure the performance of two tests: Mantoux test
and an in vitro assays (T-SPOT-TB).
The USPSTF recommendation to screen asymptomatic high-risk children for TB is based on the effectiveness of early intervention (14 controlled trials) and the accuracy of the Mantoux test
Children with a positive mantoux test
are referred to the Children's TB clinic at Starship Hospital.
PASSAR screens, level-of-care verification, physicians' orders, and Mantoux test
results for tuberculosis are just a few examples of required documentation, some of which can significantly affect payment if not obtained properly.