Lieberman coauthored one of a handful of studies comparing the immunogenicity of the MMVR injection with the standard two-shot MMR II
and varicella immunizations.
In a randomized, multicenter study, 480 healthy children received either MMR II
plus Varivax (VV) or the quadrivalent vaccine (MMRV) plus a placebo.
The FDA approved the quadrivalent vaccine for children between the ages of 12 months and 12 years, including those who are in need of a second dose of the MMR II
Infants aged 12 months showed significantly less pain based on a visual analog scale (VAS) when they received the Priorix vaccine compared with the MMR II
vaccine, said Dr.
Vaccines containing gelatin as a stabilizer include those against measles-mumps-rubella (MMR II
), varicella (Varivax), rabies (RabAvert), Japanese encephalitis (Biken), and yellow fever.