The letter notes that as long as one understands the difference between the iodine spot test without a loading dose
and the 24-hour iodine loading test, there will be no confusion between "whole-body iodine sufficiency" and "iodine sufficiency."
Our patient developed acute digoxin toxicity after a standard loading dose
of 0.01 mg/kg (1).
Details of a week-long, 2-dose loading dose
strategy is provided in the package insert." It may be safe to use a more aggressive loading dose
In our study, LS infusion was administered in a different from previous studies (22) way to all patients ata rate of 0.1 [micro][g.sup.-1] [kg.sup.-1]min without loading dose
. The findings in groups 1 and 2 were similar to results of Rajek et al.
Twelve weeks after a loading dose
of ferric gluconate, the mean TSAT level increased significantly to 29.1% [+ or -] 11.7% (P = .052), whereas there was no significant increase in serum ferritin, which was 572 [+ or -] 321 ng/mL at baseline and 706 [+ or -] 304 ng/mL at week 12 (P = 0.114) (see Figure 2).
The clopidogrel loading dose
did not contribute to this difference; the median loading doses
were 300 and 600 mg in men and women, respectively.
Nonemergent loading doses
of fosphenytoin typically range from 10 mg to 20 mg PE/kg by intramuscular injection and 15 mg to 20 mg PE/kg for emergent loading doses
to be given intramuscularly when intravenous access is impossible (Pfizer, 2002).
Recent observational data has suggested that triple antiplatelet therapy with aspirin, a thienopyridine derivative, and a Gp IIb/IIIa antagonist for PCI may be associated with an unacceptably high incidence of thrombocytopenia measured at 24% with a 300 mg loading dose
of clopidogrel (Dillon and others 2000).
This loading formula is also applicable to supplementary ("booster") loading to reach a higher serum level quickly, either because the initial loading dose
did not achieve the intended level or because that level was inadequate to control seizures.
A 100-gram loading dose
is administered followed by blood levels drawn at 30 minutes (optional) one, two and three hours.
* Recommended Dosage: Subcutaneous 40-mg loading dose
, followed by a 10-mg subcutaneous injection daily, adjusting dose based on serum insulin-like growth factor-I (IGF-I) levels, with dose not to exceed 30 mg a day.
Doctors there decided to determine if a loading dose
of acetaminophen can safely decrease the amount of time it takes for the drug to work.