The interstitial region appeared to have only a few fusiform cells that appeared to be immature
Leydig cells (Figure 3), a finding which is consistent with LCH phenotypes and confirmed the diagnosis of LCH.
The values of primary testis volume, absolute Cavalieri testis volume, the volume of seminiferous tubule epithelium and lumen, the significant increase (P=0.008) in the total number of
Leydig cells compared to the control group.
Otherwise, the body is composed of dense collagenous connective tissue and interwoven and branching bundles of smooth muscle cells (the columellar muscle) and interspersed
Leydig cells (Fig.
Well-differentiated SLCTshows open Sertoli cell tubules admixed with abundant clusters of
Leydig cells with intracytoplasmic Reinke crystals (A, arrowheads).
A slight decrease in Sertoli cells, and an atrophy of
Leydig cells.
hCG stimulation testing is used to assess a child with bilateral cryptorchidism for evidence of functioning
Leydig cells. Testosterone, DHT, and androstenedione can be measured before and after hCG stimulation.
Based on evidence showing the interaction between these systems in different cells, the aim of the present work was to study the relationship between the actions of NO and ATP-evoked purinergic currents in mice
Leydig cells with the whole cell patch clamp technique.
Especially, the administration of ND in male often accomplishes impaired spermatogenesis, depletion of
Leydig cells, and germ cell sloughing in the testis [6], atrophic change of prostate [7], and reduction of fertility [8].
Carlier, "
Leydig cell origin of testicular carcinoid tumour: immunohistochemical and electron microscopic evidence," Histopathology, vol.
SLCTs contain Sertoli and
Leydig cells which are somatic cells found within the male gonad.
A second population of
Leydig cells with round nuclei and abundant eosinophilic cytoplasm was interspersed throughout the neoplasm (Figure 4).
This correlation could be the result of the higher circulating leptin levels observed in obese or overweight men leading to a decreased testosterone production by
Leydig cells, which is able to interfere with the normal cycle of spermatogenesis [15].