LCH is a rare disease characterized by neoplastic proliferation of Langerhans cells
in various organs.
The increase in Langerhans cells
in the subbasal plexus continued (Figure 3).
sarcoma arising from chronic lymphocytic lymphoma/small lymphocytic leukemia: lineage analysis and BRAF V600E mutation study.
Similar to Langerhans cells
located in the skin, they express histiocytic markers such as S100, CD1a, and CD68 and contain Birbeck granules, which are rod-shaped intracytoplasmic organelles best demonstrated on electron microscopy.
Skeletal involvement in Langerhans cell
histiocytosis (LCH) is a rare proliferative disorder with unknown etiologies.
Histiocytosis (LCH) is an uncommon multisystem disorder of unknown etiology, characterized by accumulation of histiocytes in various tissues.
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histiocytosis with vulvar involvement and responding to thalidomide therapy Case report," Anais Brasileiros de Dermatologia, vol.
Amagai, "External antigen uptake by Langerhans cells
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(LCs) are the subset of myeloid dendritic cells that populate the epidermal layer of the skin.
On the basis of cell surface markers and intracellular molecules, different subtypes of skin DCs (Langerhans cells
, dermal DC, plasmacytoid DC, and inflammatory dendritic epidermal cells) can be distinguished.
Histopathological examination revealed bony destruction consisting of Langerhans cells
with nuclear grooves accompanied by eosinophils and lymphocytic infiltration (Figures 2(a) and 2(b)).