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Related to LMNA: progeria


See: Interest During Construction
Copyright © 2012, Campbell R. Harvey. All Rights Reserved.

Intangible Drilling Costs

Expenses a company has when it drills for oil or natural gas. Intangible drilling costs are sometimes convenient for a company's tax purposes because it can deduct intangible drilling costs in one year when the company perhaps found little or no oil from profits made in a different year when the company does find oil.

Interest During Construction

In project finance, the interest that accumulates on a loan that finances the construction of a building or development. The IDC is a cost for the project, though it is not always calculated as such. The IDC is calculated until the project begins to generate revenue, when the company financing the project begins to service its debts.
Farlex Financial Dictionary. © 2012 Farlex, Inc. All Rights Reserved
References in periodicals archive ?
2-4, 8, and 15-18, LMNA gene mutations were screened via direct sequencing of polymerase chain reaction (PCR) products.
Hegele, "LMNA is mutated in Hutchinson-Gilford progeria (MIM 176670) but not in Wiedemann-Rautenstrauch progeroid syndrome (MIM 264090)," Journal of Human Genetics, vol.
Different mutations in Lmna can produce different diseases, involving the skeleton, muscle, fat and many types of cell and tissue abnormalities, prompting lamin A/C functional diversity.
Chief researcher Professor Chris Hutchison said: "Mutations in LMNA cause more diseases, such as muscular dystrophy, than any other.
. The LMNA gene produces the Lamin A protein, which is the structural scaffolding that holds the nucleus of a cell together.
To explain this phenomenon Steen and Collas have suggested the presence of a signaling mechanism that derepresses the LMNA gene in response to a mislocalization of lamin B at the end of mitosis.
We describe a patient with limb girdle muscular dystrophy with evidence of a D596N novel mutation of the LMNA gene.
2003), the Lamin A/C gene (LMNA) (De Sandre-Giovannoli et al.
Lamins A and C are coded by a single developmentally regulated gene designated LMNA; lamin C is a splice variant and lacks the carboxyl terminus present in lamin A.
Mutations on the LMNA or lamin A gene make the lamin A protein, the structural scaffolding that holds the nucleus together, unstable.
le Dour et al., "LMNA mutations induce a non-inflammatory fibrosis and a brown fat-like dystrophy of enlarged cervical adipose tissue," The American Journal of Pathology, vol.