Has Quick or Owren prothrombin time method the advantage in harmonization for the International Normalized Ratio
Evaluation of frozen plasma calibrants for enhanced standardization of the international normalized ratio
(INR): a multi-center study.
The international normalized ratio
during concurrent warfarin and argatroban anticoagulation: differential contributions of each agent and effects of the choice of thromboplastin used.
A simple system for the derivation of international normalized ratios
for the reporting of prothrombin time results with North American thromboplastin reagents.
The intervention groups were a warfarin group (goal: international normalized ratio
[INR], 2.8-4.3) and a warfarin plus aspirin group (goal: INR, 2-2.5, plus 75 mg of aspirin daily).
Arguments for the recommended mean normal prothrombin time to calculate the international normalized ratio
. Thromb Haemostasis 1994;72:487-8.
After acute myocardial infarction, subjects were assigned to receive an antithrombotic therapy, either aspirin (162 mg daily) alone, or aspirin (81 mg daily) plus warfarin, adjusted to keep the international normalized ratio
at 1.5 to 2.5.
MELD uses serum creatinine, serum bilirubin, and the international normalized ratio
for prothrombin time, whereas DF uses prothrombin time in seconds and serum bilirubin.
The drug-food interaction was manifested by a rise in the international normalized ratio
to levels far outside the therapeutic range, resulting in a markedly increased risk of bleeding.
Background Initiation of warfarin therapy usually takes 4 to 5 days, until a therapeutic international normalized ratio
(INR) has been maintained for 2 consecutive days.
The author indicated that a meta-analysis or systematic review was not possible because of variations in study design and differences in measuring the level of anticoagulation (international normalized ratio
[INR] vs prothrombin time ratio [PTR]).
Patients on warfarin who are placed on moderate- or high-dose acetaminophen--say, at least 2 g/day--need to step up the frequency of international normalized ratio
(INR) monitoring in expectation that they will likely need a downward warfarin dose adjustment, said Dr.