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Related to Immune rejection: Organ rejection


Refusal by a bank to grant credit, usually because of the applicants financial history, or refusal to accept a security presented to complete a trade, usually because of a lack of proper endorsements or violation of rules of a firm.
Copyright © 2012, Campbell R. Harvey. All Rights Reserved.


1. A bank's refusal to grant a line of credit. This often applies to the refusal to grant a mortgage loan to an uncreditworthy person or a business loan to someone without a proper business plan.

2. An investor's refusal to accept a security presented to him/her/it. Reasons for this include suspicion of fraud or improperly filled-out forms.

3. Refusal to provide insurance coverage because the insurance company believes that the claim describes a service or situation that the policy does not cover.
Farlex Financial Dictionary. © 2012 Farlex, Inc. All Rights Reserved


The refusal to accept a security that has been delivered by a customer or broker. A questionable certificate or an improper endorsement are reasons for rejection.
Wall Street Words: An A to Z Guide to Investment Terms for Today's Investor by David L. Scott. Copyright © 2003 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved. All rights reserved.
References in periodicals archive ?
Finally, better solutions exist to potential immune rejection. In December 1998, Harold Varmus, then head of the National Institutes of Health, acknowledged during Senate testimony that immune rejection had to be overcome before stem cells could be used for transplantation, but he suggested that we might be able to do so without resorting to autologous stem cell transplantation.
If hESC-derived hematopoietic cells prove to be a scalable way to prevent immune rejection, this will certainly benefit our approach, and could obviate the scientific rationale for patient-specific therapies that are based on adult stem cells or nuclear transfer."
There is a second technology for obtaining stem cells, one that has neither the problem of immune rejection in its future, nor -- in my opinion at any rate - the taint of a lost soul in its design.
Immune rejection is mediated by our genetic makeup, specifically the set of genes which code for a type of protein called human leukocyte antigens (HLA).
To avoid the problems of immune rejection, scientists might establish a bank of human embryonic stem cells that would match almost anyone in the population.
4) The prevention of immune rejection of transplanted cells.
There is no fully effective treatment for the conditions but the transfer to the patient of "clean cells" of their own type would ensure there would be no immune rejection.
Because animals like pigs are quite different from humans, their organs would probably trigger a very strong immune rejection.
These Shielded Living Therapeutics then produce therapeutic proteins in a programmable and durable fashion, without generating fibrosis or immune rejection. Sigilon was founded and created by Flagship Pioneering in conjunction with Daniel Anderson, Ph.D.
The transplanted stem cells would also be genetically altered to reduce the risk of immune rejection, which often complicates organ transplantation.
Based in Seattle, Universal Cells Inc is a biotech company developing, licensing and commercialising stem cell therapies that overcome immune rejection and can be used to create true off-the-shelf therapeutic products.
is a Seattle-based biotech developing and commercializing stem cell therapies that overcome immune rejection and can be used to create true off-the-shelf therapeutic products.