The findings of Surgeon-performed Us-FNAC of solitary thyroid nodule shows 10 cases (10%) were inconclusive/Non-diagnostic, 60 cases (60%) Non-neoplastic (40 adenomatous/colloid goiters, 12 hyperplastic nodules, five Hashimoto thyroiditis, three colloid cyst) and 30 cases (30%) Neoplastic lesions (follicular neoplasm 22(73.4%),
Hurthle cell adenoma 2 (6.6%), papillary carcinoma 6 (20.0%).
have studied patients with FNAB results as suspicious for follicular carcinoma or
Hurthle cell neoplasm or suspicious for malignancy, and they have found a higher prevalence of malignancy among males in comparison to females (8).
Cytoplasm is often abundant and is slightly granular and acidophilic to clear, commonly resembling a
Hurthle cell. Nuclei may exhibit mild to moderate hyperchromasia and pleomorphism, with distinct nucleoli (Figure 1, A).
The pathological examination of the surgical specimen (histological and immunohistochemical) concluded with the diagnosis of
Hurthle cell carcinoma with capsular and vascular invasion (2 foci), classifying the tumor as pT1bNx G1 L0V1Pn0.
(9,11-13) The aim of this study was to determine if there are demographic and histopathological features which may be used to differentiate HCC from
Hurthle cell adenoma (HCA).
Lenvatinib was approved in Europe in May 2015 as a treatment for adults with progressive, locally advanced or metastatic differentiated thyroid cancer (papillary, follicular or
Hurthle cell), refractory to radioactive iodine.
We report a case of APMPEE wherein the patient was also diagnosed with two different tumors: a gastrointestinal stromal tumor (GIST) and a
Hurthle cell tumor.
The prognosis of multifocal PTC was better than the prognosis for multifocal follicular or
Hurthle cell histology [16].
In the former case, the results range from differentiated tumors--papillary thyroid carcinomas (PTCs), follicular thyroid carcinomas (FTCs), and
Hurthle cell carcinomas--to the rarer poorly differentiated and anaplastic thyroid carcinomas (PDTCs and ATCs, resp.).
Hurthle cell neoplasm (HCN) of the thyroid is a variant of follicular neoplasm (FN).
The biology and the genetics of
Hurthle cell tumors of the thyroid.
A few small islands of recognizable thyroid follicular epithelium with
Hurthle cell change were entrapped within the mass and focally associated with neoplastic cells.