Table 1 List of various pro-apoptotic and anti-apoptotic factors involved in the sepsis Pro-apoptotic factors Anti-apoptotic factors BAX Bcl-2 Bcl-xs Bcl-xl, Bcl-Al BIM, PUMA, NOXA Inhibitor of apoptosis proteins FAS ligand Mcl-1 Tumour necrosis factor- a Ras factor- a BID, BAK Apoptosis-inducing factor p53 BAX=Bcl-2-associated X protein, Bcl=B cell lymphoma, BIM=Bcl-2-interacting moderator of cell death, PUMA=p53- upregulated modulator of apoptosis, NOXA=phorbol-12 myristate-l-acetate-induced protein, FAS=cell surface
Fas receptor also known as CD95L, Mcl=M cell lymphoma, Ras=rat sarcoma, BID=BH3 interacting death domain, BAK=Bcl-2 homologous antagonist killer.
Effect of Pcy on cell surface and mRNA expression of
Fas receptor in SW480 and SW620 cells.
The
Fas receptor in HIV infection: expression on peripheral blood lymphocytes and role in the depletion of T cells.
One self-destruct button, a protein called Fas or
Fas receptor, sits on the surface of most cells in the body.
The patent covers IMED's core technology; the generation of human antibody molecules that binds the human
Fas receptor.
The effects of [beta]-sitosterol on the extrinsic apoptotic programmed cell death pathway in human breast MCF-7 and MDA-MB-231 adenocarcinoma cells were examined, along with the extent of its incorporation into cellular membranes and its effects on cell growth, expression of
Fas receptor pathway proteins, and caspase-8 activity.
They successfully prevented liver failure and fibrosis in two mouse models of autoimmune hepatitis by silencing the Fas gene, which encodes the
Fas receptor.
After finishing their work, T cells turn on each other; they bind to
Fas receptors to prevent a rampage against healthy cells, as sometimes happens in the liver of alcoholics.
