The workshop on
Experimental Design was organized by Dr Mark Prescott, Dr Nathalie Percie du Sert, and Dr Viki Hurst from the National Centre for the Replacement, Refinement, and Reduction of Animals in Research (NC3Rs), UK and included presentations, demonstrations, and interactive exercises.
Two measurements were performed: a baseline thermal nociception measurement (pre-MgS[O.sub.4] for groups A and C; pre-saline for groups B and D; pre-first swim for groups A, B, E and F), on day 1 of the
experimental design; and a second measurement (post-MgS[O.sub.4] for groups E and G; post-saline for groups F and H; 24 hour post-last swim for groups A, B, E and F), on day 4 of the
experimental design; no measurements were performed on days 2 or 3.
Seven studies suggested follow-up research using
experimental design extend the duration of the treatment (Baker et al., 2014; Baker & Robinson, 2016; Bunch et al., 2014; Burris & Garton, 2007; Parr et al., 2006; Pennington et al., 2015; Rose et al., 2015).
In these studies, statistical methods are essential, and authors should strive to employ an appropriate
experimental design and statistical analyses to provide the reader with scientifically relevant and valid knowledge.
Quasi-experimental designs include an intervention in the design; however, designs do not always include a control group, which is a cornerstone to an authentic
experimental design. This type of design does not have randomization like the
experimental design (Polit & Beck, 2012).
Based on the above experimental data, taking the yield of CDCA as an index, orthogonal
experimental design of four factors' three levels was taken to optimize the extracting conditions of CDCA.
In this work, we investigate the efficiency of the recently proposed ED method called the Twilight Method
Experimental Design (TMED) [15] for extracting rich data from a one-dimensional map.
Notwithstanding the use of
experimental design to improve repeatability is reported in literature [47] for other applications, optimization in SPME is usually carried out to maximize signal intensity alone, that is, gas-chromatographic peak areas.
The
Experimental Design Manager (EDM) interacts with the RM, via querying the database, to design an experiment utilizing a series of templates and CVs.
Experimental design in the behavioral and social sciences; 4v.
From our perspective, it seems clear that many authors are not sufficiently trained in
experimental design or the importance of controlling for sources of bias in their studies.
Two models for acid activation of the bentonites were developed by using a full factorial
experimental design and central composite design.