Shaheen, MD, MPH, is Chief of the Division of Gastroenterology and Hepatology at the University of North Carolina School of Medicine and is an internationally recognized clinician, educator and investigator and is an expert on Barrett's esophagus, reflux disease and esophageal cancer
Efficacy analysis of S-1 combined with radiotherapy for locally advanced esophageal cancer
The WHO said esophageal cancer
is the eighth most common cause of cancer worldwide and one of the main causes of cancer deaths, with 400,000, nearly five percent of all cancer deaths, recorded in 2012.
From this data, we can conclude that routine CT scans alone have a low diagnostic accuracy for staging of esophageal cancer
and we should include another staging tool with CT scan to properly stage tumours and direct further treatment towards the right direction.
The patients were recruited in Department of Comprehensive Oncology, Chinese Academy of Medical Sciences Cancer Hospital (CAMSCH), including a total of 50 esophageal cancer
in-patients, between June 2012 and April 2014.
The ascending incidence of esophageal cancer
over the past two decades conformed to the change in histological type and primary tumor location.
Editor's note: The findings support the results of a clinical trial of supplementation with vitamin E and selenium which found a significant reduction in esophageal cancer
deaths among younger participants, but not among older subjects who are likelier to have precancerous lesions.
Historically, esophageal cancer
has carried a poor prognosis.
GERD can lead to Barrett's esophagus, manifested by cellular changes in the lining of the lower part of the esophagus, which can increase the risk of esophageal cancer
Food and Drug Administration recently reported 23 cases of esophageal cancer
(between 1995 and 2008) in patients using the bisphosphohate alendronate and a further 31 cases in patients using bisphosphonates in Europe and Japan, possibly indicating risk of malignancy," they noted.
But researchers who examined the incidence of esophageal cancer
in more than 80,000 people divided into two groups--those who took bisphosphonates and those who did not--found no significant difference between the incidence of esophageal cancer
in the two groups.
Reflux esophagitis is a known risk factor for esophageal cancer
, but it is not known whether bisphosphonate-associated esophagitis also predisposes patients to develop gastric cancer, said Chris R.