Bromilow, "Liver enzyme induction
and inhibition: implications for anaesthesia," Anaesthesia, vol.
The optimization of medium composition specially carbon sources which affect strangely enzyme induction
and plays a crucial role in the microbial production of chitinases and help to understand the physiology of enzyme production, recognizing the key factors, setting the best bioprocess (fermentation) conditions which pave the way for the industrial scale-up with low cost and high enzymatic yield.
This requirement of opioids in smokers group for ameliorating pain was statistically more in smokers than in the non-smokers group and the reason may be the increased metabolism of opioids by enzyme induction
This occurs at a more rapid rate when there has been enzyme induction
due to, for example, chronic alcohol use.
The result from the enzyme induction
study was consistent with a recent study in which tanshinone 1 up-regulated CYP1A2 mRNA expression in a human hepatoma cell line (HepG2) (Zhang et al.
capsici induced maximum production of the enzyme in lower leave and stems on the sixth day, that is in the challenge-inoculated set of plants, the enzyme induction
was highest on six days after inoculation.
Dose dependent extent of microsomal enzyme induction
by aldrin and dieldrin in rats.
Our mild increases in enzyme activities may be explained as follows: besides enzyme induction
caused by DDT as a xenobiotic, the AST mild increase was attributed to the muscular exercise involved in the spraying activity; that of amylase was the result of the starch-rich millet-cassava diet made more prevalent by spray wages, and the GGT was because of increased consumption of lira-lira, a potent gin which is very popular in Northern Uganda.
These results are consistent with a mechanism involving complex-mediated reduction of carcinogen uptake, and do not support a role for phase II enzyme induction
in vivo under these conditions.
With 1.5% arabinose enzyme induction
was evident in 24 hours but in 48 h there was no enzyme activity.
Acute exposure of cells to Pb (10 [micro]M) was found to inhibit processes involved in glucocorticoid-mediated enzyme induction
(e.g., tyrosine aminotransferase activity) in a dose-dependent manner at both the transcriptional and translational level without altering glucocorticoid receptor binding characteristics.