In ECASS and ECASS II, patients were enrolled 0-360 min from symptom onset.
In NINDS, ATLANTIS, ECASS II, ECASS III, and EPITHET, patients in the alteplase group were assigned to receive a total intravenous dose of 0*9 mg/kg bodyweight (90 mg maximum) whereas in ECASS I the total dose was 1*1 mg/kg (100 mg maximum).All studies gave 10% of the dose as a bolus during the first minute.
(4) The ECASS
III trial found tPA to be effective when provided up to 4.5 hours after stroke onset (OR 1.34, 95% CI 1.02 - 1.76, p=0.04).
To date, L-3 has configured the ECASS
for multiple durability tests, the most recent of which was performed in the spring of 2009.
L-3 ES recently announced that it has been awarded a contract from the Swedish Defense Material Administration (FMV) for the installation and test of an ECASS
on a Swedish tactical vehicle.
During recent Tardec-funded tests at Yuma Proving Grounds, Army Hummers with Ecass
were reported as having a threefold increase in cross-country speed (both steady state and dash) with a simultaneous five to tenfold improvement in platform stability.
Under the terms of this contract, AAI has agreed to design and build 49 MEKs, the RF test subsystems, for Lockheed Martin's eCASS
test stations, which will be utilised by the Navy to test all of the critical systems, including weapons, avionics and navigation on its aircraft fleet.