For all of these reasons, ethicists, health care researchers and social scientists have begun to examine how best to ensure that strategies for tackling drug resistance
are ethically responsible.
The current study was planned to determine the prevalence and drug resistance
patterns of MDR-TB in retreatment cases in Punjab.
This phenomenon, called "growth bistability," occurred as quantitatively predicted by the researchers' mathematical models, in terms of both the dependence on the drug dose, which is set by the environment, and on the degree of drug resistance
a strain possesses, which is set by the genetic makeup of the strain and is subject to change during evolution.
These 'preventable' cases of drug resistance
provide important lessons; avoiding these mistakes will advance clinical practice and benefit patients.
Simpler regimens using fixed-dose combinations have made it much easier for people to adhere to antiretroviral treatment, limiting the spread of drug resistance
in recent years," said Gottfried Hirnschall, MD, MPH, director of WHO's HIV Department.
Talking about the drug resistant cases in Qatar, Dr Abdul Latif al Khal, consultant and director of the Medical Education Centre at Hamad Medical Corporation, said, "We are seeing an increase in drug resistance
among bacteria causing urine infection.
Now, those discoveries and the generations of drugs that followed them are at risk, as high levels of drug resistance
threaten their effectiveness, WHO said in a statement.
The strains that are resistant to the two main first line anti TB drugs that form the back bone of short course chemotherapy, isoniazid and rifampicin are known as multi drug resistance
Continuous, routine drug resistance
surveillance for all suspected TB cases has since been implemented in Tugela Ferry and >500 XDR TB cases have been diagnosed; >90% of patients are coinfected with HIV.
Pharmaceutical companies have the unique opportunity to influence the quality of drugs after manufacturing, marketing and sales through better packaging and inserts that inform patients and dispensers about appropriate use, as well as through better monitoring of supply chain conditions (to avoid the degradation of drugs and the introduction of poor products), and by educating dispensers and prescribers about drug resistance
Guided by a resiliency framework (Waller, 2001), the purpose of this study was to examine the culturally specific drug resistance
strategies used by Hawaiian youth in rural communities in Hawai'i.
One of the main causes of failure in the treatment of cancer is the development of drug resistance
by the cancer cells.