Lead and methyl mercury: effects of acute exposure on cytochrome P450
and the mixed function oxidase system in the liver.
Potent inhibition by star fruit of human cytochrome P450
3A (CYP3A) activity.
It has been found that aromatic nitrogen group is the more likely inhibitor of cytochrome P450
isozymes due to its lipophilicity and ability to maintain hydrogen bonding with the CYP isoforms and decreasing their iron binding capacity .
Glutathione S-transferase and cytochrome P450
(general oxidase) activity levels in Candidatus Liberibacter asiaticus-infected and uninfected Asian citrus psyllid (Hemiptera: Psyllidae).
epoxygenase promotes human cancer metastasis.
Inhibition of human cytochrome P450
activities by kava extract and kavalactones.
and Simpson and Boyd then reconstituted the steroid 11[beta]-hydroxylation system and the cholesterol side-chain cleavage system, respectively, and suggested the sequence of electron transfer from NADPH to cytochrome P450
via adrenodoxin and the reductase.
Effect of Cantharidin on Activity of Cytochrome P450
The review found that in many cases, hepatotoxicity could be attributed to predisposing factors such as a genetic defect in hepatic microsomal cytochrome P450
deficiency or could have been the result of co-administration of kava and pharmaceutical drugs (Teschke 2003).
The scientists narrowed down the potential genetic culprits to members of a family of genes coding for enzymes known as cytochrome P450s
Many drug interactions are caused by cytochrome P450
activity or inhibition.
Sandson says this is a second edition of Drug Interactions Casebook: The Cytochrome P450
System and Beyond (no date or publisher noted); the publisher says this is a first edition.