Therefore, it may be supposed that the effect of hydrogen bonds on the ligand affinity to the cytochrome P450
active site is not of primary importance.
Metabolism of the human immunodefiency virus protease inhibitors indinavir and ritonavir by human intestinal microsomes and expressed cytochrome p450
3A4/3A5: mechanism - based inactivation of cytochrome p4503A by ritonavir.
Thomas, "Rapid birth-death evolution specific to xenobiotic cytochrome P450
genes in vertebrates," PLoS Genetics, vol.
Guengerich, "Complex reactions catalyzed by cytochrome P450
enzymes," Biochimica et Biophysica Acta (BBA)--General Subjects, vol.
A passion for P450s (rememberances of the early history of research on cytochrome P450
Glutathione S-transferase and cytochrome P450
(general oxidase) activity levels in Candidatus Liberibacter asiaticus-infected and uninfected Asian citrus psyllid (Hemiptera: Psyllidae).
epoxygenase promotes human cancer metastasis.
Evidence for a role of a perferryl-oxygen complex, Fe03+, in the N-oxygenation of amines by cytochrome P450
By making small, precise changes to cytochrome P450
, Biocatalysts were able to identify a form that is able to react with valencene.
They found the pigment to be a hemoprotein and named it cytochrome P450
(P450), i.e., the pigment (P) with a spectral absorbance maximum at 450 nm in the presence of carbon monoxide and a reducing agent.
The Bumpus laboratory studies how drugs are processed in cells by enzymes of the cytochrome P450