Molecular cloning of endopin 1, a novel serpin localized to neurosecretory vesicles of chromaffin cells
Resection of chromaffin cell
tumor will completely relieve the symptoms.
Below of the reticular zone, centrally in the organ, the medullar region comprising large chromaffin cells
and numerous blood vessels was found (Figure 4).
Pheochromocytoma and Paraganglioma originates from chromaffin cells
of adrenal medulla and autonomic paraganglia, which are both derived from the neural crest cells.
There are probably other neurohumoral agents secreted by the tumor chromaffin cells
, such as neuropeptide Y, that can act synergistically with the catecholamines and worsen the myocardial injury and the patient's progress.
Tympanic paragangliomas are neuroendocrine neoplasms located in the middle ear and arising from chromaffin cells
of the parasympathetic paraganglia.
A phaeochromocytoma is a rare neuro-endocrine tumour of the paraganglionic chromaffin cells
affecting 2-8 persons per million per year.
The specific aims of this proposal are: 1) to characterize the alpha6-containing nAChR subtype(s) present in human adrenal chromaffin cells
and to investigate the regulation of their expression by nicotine; 2) to study the functional interaction between alpha6beta4 nAChRs and mitochondria; 3) the regulation of this nAChR subtype by mitochondrial ROS.
Unlike CV in the urchin egg, secretory vesicles of chromaffin cells
are concurrently present at various stages of secretory readiness.
Cathecolamines (epinephrine and norepinephrine) and more than thirty biologically active peptides (neuropeptide Y, dopamine, chromogranins A, B, C, methionine, calcitonin gene-related peptide, leucine, enkephalin, substance P, synaptophysine, endotelins, adrenomedullin, interleukin-1) are stored in coated granules within the chromaffin cells
and are delivered through cellular depolarization and exocytosis via adrenal vein into the circulating blood (Colomer 2009).
PCCs are rare catecholamine-producing tumours thought to arise from chromaffin cells
in the adrenal medulla.
Rapid sprouting of filopodia in nerve terminals of chromaffin cells
, PC12 cells, and dorsal root neurons induced by electrical stimulation.