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The Duffy blood group antigens, also called Duffy antigen receptor for chemokines (DARC), recently renamed atypical chemokine receptor 1 (ACKR1).
Genotyping of atypical chemokine receptor 1 was performed using a 5'-nuclease assay with TaqMan-minor groove binding probes.
2001) CC chemokine receptor (CCR)4 and the CCR10 ligand cutaneous T cell-attracting chemokine (CTACK) in lymphocyte trafficking to inflamed skin.
The report provides a snapshot of the global therapeutic landscape for C-C Chemokine Receptor Type 5 (C-C CKR-5 or CHEMR13 or HIV-1 Fusion Coreceptor or CD195 or CCR5)
Gq-deficient (Gnaq-/-) DCs and monocytes are unable to migrate to inflammatory sites and lymph nodes in vivo, demonstrating that this alternative Gq-coupled chemokine receptor signaling pathway is critical for the initiation of immune responses [32, 38].
HIV-1 and HIV-2 strains have been reported to be capable of utilising several alternative chemokine receptors, including CCR2b, CXCR4, CXCR6 and GPR1, to mediate infection of cells.
Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-kappaB activation in breast and pancreatic tumor cells.
CC chemokine receptor 5 polymorphism in Italian patients with giant cell arteritis.
The CC chemokine receptor 4 as a novel specific molecular target for immunotherapy in adult T-Cell leukemia/ lymphoma.
Since lymphocytes must be positioned correctly to interact with other cells, the pattern of chemokine receptors, the type, and distribution of chemokines in tissues critically influence immune responses.
It is a short peptide that functions as a high-affinity antagonist for CXCR4, a chemokine receptor that is directly involved in tumor progression, angiogenesis (growth of new blood vessels in the tumor), metastasis (spread of the disease to other organs or organ parts) and cell survival.
Resistance to HIV1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene.