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To detect the role of ginsenoside Rg1 in the migration of human renal tubular epithelial cells, HK-2 cells were treated with LPS and/or 150 [micro]m ginsenoside Rg1, and then cell migration was assessed.
The standard cell migration model also ignores the fact that there are a lot of other cells in the way as the migrating cell cluster travels from one end of the egg to the other.
In this study, the effects of novel peptide derived from abalone (Haliotis discus hannai) on cancer cell migration were investigated using MKN-28 gastric cancer cells.
Still, Yao's early findings suggest that the use of electrical fields in cell migration could become a burgeoning area of study in regenerative medicine.
F-actin dynamics is essential for alteration of cytoskeleton during cell migration and invasion [30].
Because dHACM was demonstrated to promote the proliferation of stem cells, the closure of the cell-free zone observed is likely a result of a combination of both stem cell migration and proliferation.
The findings, published in the March 13, 2015, edition of Nature Communications, shed light on the mechanisms of cell migration, particularly in the wound-healing process.
As to cell migration the results show that Vitronectin enhance cell migration across the membrane of transwell chamber.
But when their functioning is altered, as the UCL researchers observed in tumor cells, the mitochondria can promote cell migration, thus leading to the formation of metastasis.
Professor Chris Bunce, research director at Leukaemia & Lymphoma Research, said: "is innovative model provides important new opportunities for the study of new drugs that target molecules involved in cancer cell migration and homing.