However, when the impact factor dropped to a certain extent, it would influence the experimental results in Figure 7: the expression of the cell cycle protein was no longer cyclical (cell cycle damage: the cells are not split); we could analyze the cells effects of internal factors in cell division cycle
The previous studies suggested that Cdc25 homologues control the entry into mitosis through dephosphorylating and activating specific substrate cyclin-dependent kinases (CDK) to regulate the progression of cell division cycle
and transition (Gould and Nurse, 1989; Dunphy and Kumagai, 1991; Gautier et al., 1991; Millar et al., 1991; Strausfeld et al., 1991; Lee et al., 1992).
The compound, which specifically inhibits mitotic kinesin Eg5, arrests the cell division cycle
of cancer cells at the mitotic phase and induces apoptosis.
An example of the TraFaC output for cell division cycle
25a (CDC25A) is shown in Figure 4.
Functional of metal-ion homeostasis in the cell division cycle
, mitochondrial protein processing, sensitivity to mycobacterial infection and brain function.