However, when the impact factor dropped to a certain extent, it would influence the experimental results in Figure 7: the expression of the cell cycle protein was no longer cyclical (cell cycle damage: the cells are not split); we could analyze the cells effects of internal factors in
cell division cycle.
The previous studies suggested that Cdc25 homologues control the entry into mitosis through dephosphorylating and activating specific substrate cyclin-dependent kinases (CDK) to regulate the progression of
cell division cycle and transition (Gould and Nurse, 1989; Dunphy and Kumagai, 1991; Gautier et al., 1991; Millar et al., 1991; Strausfeld et al., 1991; Lee et al., 1992).
The compound, which specifically inhibits mitotic kinesin Eg5, arrests the
cell division cycle of cancer cells at the mitotic phase and induces apoptosis.
An example of the TraFaC output for
cell division cycle 25a (CDC25A) is shown in Figure 4.
Functional of metal-ion homeostasis in the
cell division cycle, mitochondrial protein processing, sensitivity to mycobacterial infection and brain function.
