Receiver-operating characteristic curves for prostate cancer antigen
3 (PCA3) and prostate-specific antigen (PSA) in (A) the whole study
HE4, human epididymis secretory protein 4; CA125, cancer antigen
125 Table 6: Diagnostic performance of classical risk of malignancy indices (RMIs) 1-4 in patients with adnexal masses.
 Nonstandard abbreviations: PDAC, pancreatic ductal adenocarcinoma; CUZD1, CUB and zona pellucida like domains protein 1; CA19-9, cancer antigen
19-9; TBST, Tris-buffered saline with Tween 20; MS, mass spectrometry; SEC, size-exclusion chromatography.
The granted United States Patent protects additional cancer antigens
which Cancer Vac can use in the commercialization of its immunotherapy program.
(Tokyo, Japan) has patented a tumor antigen gene identified by screening a cDNA library derived from a gastric cancer cell line that can induce gastric cancer antigen
specific cytotoxic T cell by means of hybridization and PCR utilizing an amino acid sequence of peptide fragment of a known gastric cancer antigen
protein, introducing a selected cDNA clone into a cell of gastric cancer cell line that cannot induce gastric cancer antigen
specific cytotoxic T cell so that the clone should be expressed in the cell, and selecting a transgenic cell that has acquired the ability to induce cytotoxic T cell.
"Our achievement of this milestone represents continued advancement of our lung cancer antigen
discovery program," said Steven Gillis, Ph.D., chairman and chief executive officer of Corixa.
A case of benign multicystic mesothelioma of the peritoneum (BMMP) is presented uniquely characterized by an elevated serum carbohydrate antigen 19-9 (CA-19-9) and biopsy positive immunostaining for CA-19-9, carcinoembryonic antigen (CEA), and cancer antigen
The 125th promising clone was designated OC125 (for ovarian cancer 125), and the cancer antigen
recognized by this antibody became CA125.
Gen-Probe claims its Progensa test, which screens urine samples for prostate cancer antigen
3, can better differentiate between malignancies and other conditions that create the false positives in the traditional PSA blood test.
Results from the last--the PLCO (Prostate, Lung, Colorectal, and Ovarian) trial, which tested screening with cancer antigen
125 (CA125) and transvaginal ultrasound--were recently reported (JAMA 2011;305:2295-303).
San Antonio -- Elevated cancer antigen
125 levels measured after surgery but before chemotherapy are an independent prognostic indicator of recurrence and worse survival in women with high-risk, early-stage epithelial ovarian cancer, according to results of a Gynecologic Oncology Group study.
Occasionally, we see a patient with a family history of ovarian cancer who requests a test for cancer antigen