Taking a calcium channel
blocker is like removing your thumb from the hose opening, and pressure is decreased.
The results of our study showed that treatment with calcium channel
blockers (CCBs), particularly amlodipine, is not related to purpura or bleeding.
Recent literature has described the successful reversal of ten separate drug class toxicities by Intralipid emulsion rescue therapy, including amphetamines (3), antiarrhythmics (4), anticonvulsants (5), antidepressants (5), antipsychotics (6), benzodiazepines (5), calcium channel
blockers (1), diuretics (5), local anesthetics (7-9), and the benzodiazepine-agonist insomnia drugs (Table 1).
This calcium channel
turns out to be a key player in normal sleep.
blocking agents like verapamil, nifedipine and diltiazem are commonly used in the treatment of hypertension, angina, myocardial infarction and supraventricular tachycardia.
Kerns II, "Management of beta-adrenergic blocker and calcium channel
antagonist toxicity, "Emergency Medicine Clinics of North America, vol.
While two of the calcium channel
blocker intoxication patients were poisoned by accident, five patients ingested the drug for the aim of suicide.
Overall, Haas and colleagues affirm current practice, concluding that prostaglandin inhibitors (eg, indomethacin) and calcium channel
blockers (eg, nifedipine, nicardipine) delay delivery and improve short-term neonatal outcomes, whereas beta-agonist therapy was not considered to be as preferable, largely due to its maternal side effect profile.
Calcium salts increase the concentration of calcium ions in blood and cardiac muscle, thus improving contractility strength and antagonizing the effects of calcium channel
Dose-finding study with nimodipine: a selective central nervous system calcium channel
blockers on aminophylline induced seizure model in rats.
More recently, a secondary analysis of the 19,257-subject ASCOT (Anglo-Scandinavian Cardiac Outcomes Trial) demonstrated that calcium channel
blocker-based antihypertensive therapy was particularly effective against stroke in the population most in need of such protection: the elderly.
The researchers found that a cheap diuretic ("water pill") was more effective than a calcium channel
blocker in preventing heart failure.