Nevertheless, this patient was treated by glucocorticoid and ambrisentan, an oral endothelin-receptor antagonist, and then her symptoms improved obviously meanwhile pulmonary systolic pressure decreased, which indicated PCH associated with CREST syndrome
might response to oral drug therapy and avoid lung transplantation.
However, taking into consideration this recent diagnosis, the immunosuppressive treatment with cyclosporine for CREST syndrome
To improve sensitivity for milder forms of disease, the condition is often divided into diffuse systemic scleroderma (dSSc) or limited systemic scleroderma (lSSc) (TABLE 1), with CREST syndrome
being a variant of the limited form.
4) Finally, many systemic diseases can lead to auricular ossification, including congenital plaque-like osteomatosis, Albright hereditary osteodystrophy, fibrodysplasia ossificans progressiva, Addison disease, osseous heteroplasia, and collagen vascular diseases, especially CREST syndrome
and childhood dermatomyositis.
We report the rare case of a male patient with CREST syndrome
accompanied by PBC, manifested by acute cholecystitis and mild jaundice.
Gareth Davies, 47, was working in the south east Asian country when he was struck down with wasting disease CREST syndrome
13] However, the local anesthetic effect is too short to explain lasting relief, and a randomized controlled study of injection therapy of the iliac crest syndrome
showed no difference in pain outcome between lidocaine hydrochloride and saline.