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The process of settling transactions. Most exchanges have one or more clearing houses, which are charged with matching orders together, ensuring that deliveries are made to the correct parties, and collecting margin money. Because so many trades take place on an exchange in a given day, clearing houses exist to process what each party owes or is owed in a central location so the fewest securities actually change hands. For example, suppose that a broker-dealer buys 1000 shares of a security and then, in a completely separate transaction, sells 700 of the same shares. At the end of the trading day, the clearing house would determine that the broker-dealer must only buy 300 shares as the other 700 belong to another party. Clearing houses receive a clearing fee in exchange for clearance services.
Farlex Financial Dictionary. © 2012 Farlex, Inc. All Rights Reserved


Clearance is the first half of the process that completes your order to buy or sell a security. During clearance, the details on both sides of the transaction are compared electronically to ensure that the order to buy and the order to sell correspond.

For example, in a stock transaction, the Committee on Uniform Securities Identification Procedures (CUSIP) number, the number of shares, and the price per share must match.

Next, transactions within each broker-dealer are netted down, or offset, by matching its clients' buy orders against sell orders from others of its clients or among a group of affiliated firms. Their records are then updated to reflect the new ownership and account balances.

Any unmatched orders are forwarded to the National Securities Clearing Corporation (NSCC), which instructs selling broker-dealers to provide the relevant securities and the buying broker-dealer to send the cash.

Dictionary of Financial Terms. Copyright © 2008 Lightbulb Press, Inc. All Rights Reserved.
References in periodicals archive ?
List of Abbreviations IA-TXA: Intra-articular tranexamic acid PBL: Perioperative blood loss TKR: Total knee replacement BT: Blood transfusion THL: Total hemoglobin loss ETBL: Estimated total blood loss DV/kg: Drainage volume per kg Hb: Hemoglobin BMI: Body mass index TXA: Tranexamic acid OA: Osteoarthritis KL: Kellgren and Lawrence ROM: Range-of-motion ASA: American Society of Anesthesiologists aPTT: Activated partial prothrombin time INR: International normalized ratio CrCl: Creatinine clearance CCI: Charlson Comorbidity Index.
FDA-approved labeling for prescription rantidine recommends a dose of 150 mg ranitidine orally every 24 hours for patients with a CrCl less than 50 mL/minute, which coincides with the OTC labeled dose (GlaxoSmithKline, 2009).
So we recommend MDRD equation in preference to Cockcroft Gault's CrCl equation to be used for estimation of GFR in clinical practice in young healthy Pakistani population.
Two hundred and twenty-seven (2.2%) of the 10 416 patients who had creatinine concentrations recorded at baseline started tenofovir despite a CrCl <50 mL/min.
The GFR used to be estimated by CrCl in 24-h urine but this is a time-consuming and imprecise method.
This would result in Crcl values being higher leading to over estimation of GFR.
(47) The FBI is also a member of the Incident Coordination Communications Team managed by DHS CRCL.
Choose: Tirofiban Dose: Bolus-Only Strategy: 0.25 mcg/kg, or Standard regimen: IV infusion of 0.4 [micro]g/kg/min for 30 min (reduce to 0.2 [micro]g/kg/min for CrCl <30 mL/min), followed by IV infusion of 0.1 [micro]g/kg/min for 18-24 hours (reduce to 0.05 [micro]g/kg/ min if CrCl <30 mL/min).
The phase III ROCKET AF (Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation) study compared rivaroxaban (20 mg od; 15 mg od in patients with CrCl 30-49 mL/min) with dose-adjusted warfarin for stroke prevention in patients with nonvalvular atrial fibrillation [12].
Clinical findings of rheumatoid arthritis patients with pancytopenia due to methotrexate Case Age/ Treatment MTX Drugs Risk factors gender duration weekly (years) dosage (mg) 1 60/F 1 7.5 Not reported CrCl <50 ml/min Hypoalbuminemia Dehydration Infection 2 59/M 1 15 Digoxin Infection CrCl Furosemide <50 ml/min Dipyridamole Indomethacin 3 71/F 5 10 MTX Diclofenac CrCl <50 Clopidogrel ml/min Old age Hypoalbuminemia Dehydration Infection Daily MTX High MCV value Case Bone marrow Peripheral findings eosinophil increase (days after admission) 1 Relative increase in 4th eosinphil, and dyserythropoiesis 2 Bone marrow 1st eosinophilia (40%), and dyserythropoiesis 3 Bone marrow 5th eosinophilia (50%) Case numbers 1 and 2 show results from the study by Bruyn et al.
Adequate renal function defined as a calculated Creatinine Clearance (CrCl) greater than 60 ml/min as estimated by the Cockcroft- Gault equation
Creatinine clearance (CrCl) has been the most widely used measure of GFR and requires the complete timed collection of urine as well as a blood sample for S-Cr (taken during the urine collection period).