CML


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CML

Copyright © 2012, Campbell R. Harvey. All Rights Reserved.

Capital Market Line

In the capital asset pricing model, a line that plots the extra return an investor expects for each change in the level of risk. Rational investors expect higher returns for riskier assets and the capital market line shows this graphically. A portfolio that accurately reflects the capital market line is considered a Markowitz efficient portfolio. The slope of the capital market line is a calculation of the equilibrium market price of risk. See also: Beta.
Farlex Financial Dictionary. © 2012 Farlex, Inc. All Rights Reserved
References in periodicals archive ?
Chronic myeloid leukaemia (CML) is a myeloproliferative disorder predominantly of adult life, having a male preponderance.1 These patients have variable presentations.2 Some are completely asymptomatic, their disease being diagnosed incidentally on routine blood CP while others may have symptoms due to anemia or splenomegaly.3 CML is usually diagnosed on peripheral blood film but the detection of the BCR-ABL fusion transcript by molecular techniques is necessary for establishing a definitive diagnosis.4
Further Capex Cuts: CML's pre-dividend FCF margin should expand to over 10% in 2018 as capex decreases.
Ninety two adult patients suffering from chronic-phase CML who had been on Imatinib treatment for at least 6 months were included in the study.
Our case is a unique presentation of CML blast crisis, which unfortunately has an aggressive biology.
It is evident that clinical management of patients suffering from CML has been radically reformed, especially since the introduction of TKIs to inhibit BCR-ABL.
Reasonable amount of data is available regarding the epidemiology, molecular pathogenesis, clinical manifestations, and treatment response of secondary AML and MDS; however, very little is known about therapy-related CML. Therapy-related CML cannot be distinguished from de novo cases both cytogenetically and clinically.
The genetic alteration in CML is one of the most extensively studied and best understood models in human cancer, and the treatment of CML with tyrosine kinase inhibitors has been one of the most successful stories in oncology.
Total 83 patients with CML were divided in to chronic phase (CP) 62 (74.6%), 17 (20.4%) in the accelerated phase (AP) and 3 (5.0%) in blast crisis (BC).
CML III does not address behavioral-based interview questions, nor does it have an extensive section on technology.
The brans significantly decreased levels of CML compared to the control.